PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v3.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT3G63350.1
Common NameAT-HSFA7B, F16M2.200, HSF10, HSFA7B
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family HSF
Protein Properties Length: 282aa    MW: 32623.6 Da    PI: 4.869
Description HSF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AT3G63350.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HSF_DNA-bind109.91.8e-34291212103
                   HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXXXXXXXXXXXXX CS
  HSF_DNA-bind   2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFkkgkkellekik 98 
                   Fl+k++e++ d+++++++sw++ g sfvv+d+++f+ ++Lp yFkh+nf+SFvRQLn+YgF+k++ e+         weF ++ F  g+++ll++ik
   AT3G63350.1  29 FLTKTFEMVGDPNTNHIVSWNRGGISFVVWDPHSFSATILPLYFKHNNFSSFVRQLNTYGFRKIEAER---------WEFMNEGFLMGQRDLLKSIK 116
                   9****************************************************************999.........******************** PP

                   XXXXX CS
  HSF_DNA-bind  99 rkkse 103
                   r++s+
   AT3G63350.1 117 RRTSS 121
                   **986 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.103.6E-3622113IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM004151.1E-5225118IPR000232Heat shock factor (HSF)-type, DNA-binding
SuperFamilySSF467853.61E-3325118IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF004478.7E-3129118IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000565.8E-192952IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000565.8E-196779IPR000232Heat shock factor (HSF)-type, DNA-binding
PROSITE patternPS0043406892IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000565.8E-198092IPR000232Heat shock factor (HSF)-type, DNA-binding
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009408Biological Processresponse to heat
GO:0009644Biological Processresponse to high light intensity
GO:0005634Cellular Componentnucleus
GO:0005737Cellular Componentcytoplasm
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0009005anatomyroot
PO:0009030anatomycarpel
PO:0009052anatomyflower pedicel
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 282 aa     Download sequence    Send to blast
MDPSSSSRAR SMPPPVPMEG LQEAGPSPFL TKTFEMVGDP NTNHIVSWNR GGISFVVWDP  60
HSFSATILPL YFKHNNFSSF VRQLNTYGFR KIEAERWEFM NEGFLMGQRD LLKSIKRRTS  120
SSSPPSLNYS QSQPEAHDPG VELPQLREER HVLMMEISTL RQEEQRARGY VQAMEQRING  180
AEKKQRHMMS FLRRAVENPS LLQQIFEQKR DREEAAMIDQ AGLIKMEEVE HLSELEALAL  240
EMQGYGRQRT DGVERELDDG FWEELLMNNE NSDEEEANVK QD
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
2ldu_A5e-252412312125Heat shock factor protein 1
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1111117LKSIKRR
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO184127350.0
Genevisible251166_at0.0
Expression AtlasAT3G63350-
AtGenExpressAT3G63350-
ATTED-IIAT3G63350-
Functional Description ? help Back to Top
Source Description
TAIRmember of Heat Stress Transcription Factor (Hsf) family
UniProtTranscriptional activator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE).
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT3G63350.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT3G63350
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankDQ4467840.0DQ446784.1 Arabidopsis thaliana clone pENTR221-At3g63350 heat shock transcription factor family protein (At3g63350) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_191894.10.0heat stress transcription factor A-7b
SwissprotQ9M1V50.0HFA7B_ARATH; Heat stress transcription factor A-7b
TrEMBLD7LTQ20.0D7LTQ2_ARALL; Putative uncharacterized protein
STRINGAT3G63350.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM148361619
Representative plantOGRP9617233
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Nover L, et al.
    Arabidopsis and the heat stress transcription factor world: how many heat stress transcription factors do we need?
    Cell Stress Chaperones, 2001. 6(3): p. 177-89
    [PMID:11599559]
  3. Port M, et al.
    Role of Hsp17.4-CII as coregulator and cytoplasmic retention factor of tomato heat stress transcription factor HsfA2.
    Plant Physiol., 2004. 135(3): p. 1457-70
    [PMID:15247379]
  4. Ma S,Gong Q,Bohnert HJ
    Dissecting salt stress pathways.
    J. Exp. Bot., 2006. 57(5): p. 1097-107
    [PMID:16510518]
  5. Nishizawa A, et al.
    Arabidopsis heat shock transcription factor A2 as a key regulator in response to several types of environmental stress.
    Plant J., 2006. 48(4): p. 535-47
    [PMID:17059409]
  6. Charng YY, et al.
    A heat-inducible transcription factor, HsfA2, is required for extension of acquired thermotolerance in Arabidopsis.
    Plant Physiol., 2007. 143(1): p. 251-62
    [PMID:17085506]
  7. Underwood BA,Vanderhaeghen R,Whitford R,Town CD,Hilson P
    Simultaneous high-throughput recombinational cloning of open reading frames in closed and open configurations.
    Plant Biotechnol. J., 2006. 4(3): p. 317-24
    [PMID:17147637]
  8. Guo J, et al.
    Genome-wide analysis of heat shock transcription factor families in rice and Arabidopsis.
    J Genet Genomics, 2008. 35(2): p. 105-18
    [PMID:18407058]
  9. Hanada K, et al.
    Functional compensation of primary and secondary metabolites by duplicate genes in Arabidopsis thaliana.
    Mol. Biol. Evol., 2011. 28(1): p. 377-82
    [PMID:20736450]
  10. Nishizawa-Yokoi A, et al.
    HsfA1d and HsfA1e involved in the transcriptional regulation of HsfA2 function as key regulators for the Hsf signaling network in response to environmental stress.
    Plant Cell Physiol., 2011. 52(5): p. 933-45
    [PMID:21471117]
  11. Guan Q,Lu X,Zeng H,Zhang Y,Zhu J
    Heat stress induction of miR398 triggers a regulatory loop that is critical for thermotolerance in Arabidopsis.
    Plant J., 2013. 74(5): p. 840-51
    [PMID:23480361]